Pharma 4.0, an application of Industry 4.0 concepts in the pharmaceutical industry, aims to enhance manufacturing efficiency, product quality, and consistency. It faces challenges in areas like artificial intelligence, material traceability, optimization, process control, cyber-physical security, and data management due to the complexity involved. However, by incorporating artificial intelligence and advanced model predictive control with robust cyber-physical security measures, predictive capabilities and product quality can be significantly improved. This work focuses on implementing seven Industry 4.0 components, including AI/ML, modeling, material traceability, optimization, advanced control, cyber-physical security, and data science, in continuous pharmaceutical manufacturing processes.

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